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KMID : 1189220100370020173
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Korean Journal of Reproductive Medicine
2010 Volume.37 No. 2 p.173 ~ p.179
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Case of Tamoxifen-Associated Rapid Growing and Multiple Endometrial Polyps
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Lee Hee-Jun
Kim Hoon
Ku Seung-Yup
Han Won-Shik
Kim Seok-Hyun
Choi Young-Min
Kim Jung-Gu
Moon Shin-Yong
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Abstract
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The antiestrogen tamoxifen is currently the most commonly used adjuvant treatment of breast cancer with antiestrogenic effect on mammary tissue. However, it is also associated with endometrial abnormalities, including hyperplasia, polyps, carcinoma, mostly interpreted as evidence of estrogenic effect on the endometrium. Previously, tamoxifen-associated polyp in breast cancer has been reported in the literature. Most studies had a long follow-up period and tamoxifen-associated polyp developed more than 1 year after tamoxifen treatment. In this case, we report an unusual case of rapid growing and multiple endometrial polyps that were developed only after 3 months’ tamoxifen treatment in a postmenopausal breast cancer patient who received quadrant mastectomy with a brief review of literature.
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KEYWORD
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Tamoxifen, Endometrial polyp
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