KMID : 0043319970200010093
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Archives of Pharmacal Research 1997 Volume.20 No. 1 p.93 ~ p.95
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DA-5018, a Novel Vanilloid Type Analgesic
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Park Young-Ho
Lee Sang-Sup You Eun-Sook Kim Won-Bae
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Abstract
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The aim of the present study was to elucidate the mechanism of action of DA-5018 and to compare it with those of capasaicin, resiniferatoxin (ultrapotent capasaicin analog), and olvanil (systemic antinociceptive agent equipotent with capasaicin developed by Proctor & Gamble) (fig.1).
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KEYWORD
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DA-5018, Capasaicin, Dorsal root ganglion, Neuropeptide depletion
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