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KMID : 0043319970200050516
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Archives of Pharmacal Research
1997 Volume.20 No. 5 p.516 ~ p.518
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Inhibitory Effects of Ginseng Total Saponin on Methamphetamine-induced Striatal Dopamine Increase in Mice
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Oh Ki-Wan
Kim Hack-Seang
Wagner George-C.
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Abstract
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In conclusion, biochemical analysis revealed that GTS inhibited the methamphetamine-induced DA increase and the methamphetamine-induced DOPAC decrease in the mouse striatum. These results indicate that GTS could modulate the methamphetamine-induced striatal dopaminergic neuronal systems.
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KEYWORD
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Methamphetamine Dopamine, Striatum, Ginseng total saponin
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