KMID : 0043320050280101111
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Archives of Pharmacal Research 2005 Volume.28 No. 10 p.1111 ~ p.1113
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Synthesis of 5-Aminolevulinic Acid (ALA) and Its t-Butyl Ester for the Fluorescence Detection of Early Cancer
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Kang Min-Seok
Kim Dong-Myung Kim Jeong-Sook Jeong Jin-Hyun
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Abstract
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5-Aminolevulinic acid and its derivatives, which are known to affect the early diagnosis and treatment of cancer, have been synthesized. Simple methods for the synthesis of 5-aminolevulinic acid (ALA), a precursor of porphyrins, have been developed in our laboratory for use in studies on the biosynthesis of porphyrins.
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KEYWORD
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5-Aminolevulinic acid, Fluorescence detection, ALA, PDT
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