KMID : 0043320070300020151
|
|
Archives of Pharmacal Research 2007 Volume.30 No. 2 p.151 ~ p.154
|
|
Cytotoxic Isoquinoline Alkaloids from the Aerial Parts of Corydalis incisa
|
|
Choi Sang-Un
Baek Nam-In Kim Sung-Hoon Yang Jae-Heon Eun Jae-Soon Shin Tae-Yong Lim Jong-Pil Lee Jae-Hyeok Jeon Hoon Yun Mi-Young Leem Kang-Hyun Park Hee-Wook Kim Dae-Keun
|
|
Abstract
|
|
|
Three known isoquinoline alkaloids were isolated from the chloroform-soluble fraction of the methanolic extract of the aerial parts of Corydalis incisa (Papaveraceae) through repeated column chromatography. Their chemical structures were elucidated as corynoline (1), corynoloxine (2) and 6-oxocorynoline (3) using spectroscopic analysis. Compounds 1-3 exhibited cytotoxicity against human A549, SK-OV-3, SK-MEL-2 and HCT15 tumor cells.
|
|
KEYWORD
|
|
Corydalis incisa, Papaveraceae, Isoquinoline alkaloids
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|