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KMID : 0043320070300030267
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Archives of Pharmacal Research
2007 Volume.30 No. 3 p.267 ~ p.269
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Metabolites from the Fungus Cephalosporium sp. AL031
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Bi Yun-Mei
Bi Xu-Bin
A Fang
Zhao Qian-Rong
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Abstract
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A new pyrone derivative, 7, 9-dihydroxy-10-methyl-2H, 4aH, 6H, 10bH-pyrano[5,6-c][2]benzopyran- 2,6-dione (1), was isolated from a culture broth of a strain of the fungus Cephalosporium sp. AL031, together with three known compounds, 3-acetyl-7-hydroxy-5-methoxyl-3Hisobenzofuran- 1-one (2), vermopyrone (3), and 5-methylmellein (4). Their structures were elucidated by spectroscopic analysis including MS and 2D-NMR. Compounds 2, 3, and 4 are reported for the first time from fermentation broth of this fungus through the present study.
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KEYWORD
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Cephalosporium sp., Pyrone derivative, 3-Acetyl-7-hydroxy-5-methoxyl-3Hisobenzofuran-1-one, Vermopyrone, 5-Methylmellein, Fungal metabolites
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