|
KMID : 0043320130360111311
|
|
Archives of Pharmacal Research
2013 Volume.36 No. 11 p.1311 ~ p.1318
|
|
|
Simultaneous determination of five flavonoids during the growth of Fructus Sophorae by capillary electrophoresis
|
|
Li Yu Mei
|
|
|
Abstract
|
|
|
|
A method of simultaneous determination of five flavonoids during the growth of Fructus Sophorae by β-cyclodextrin (β-CD-) modified capillary zone electrophoresis was developed. The effects of various parameters such as buffer concentration, pH, applied voltage, and β-CD concentrations were investigated. After a series of optimization processes, the determination of five flavonoids in Fructus Sophorae was successfully achieved in 20 mmol/L borax buffer (pH 9.5), 25 kV applied voltage, and 8 mmol/L β-CD. The linearity, detection limits, repeatability, and recovery were satisfactory. Thus, the proposed β-CD-modified capillary zone electrophoresis method was satisfactorily used to analyze Fructus Sophorae samples. The results can be useful for the quality control and medicinal resource development of Fructus Sophorae.
|
|
|
KEYWORD
|
|
|
Fructus Sophorae, Flavonoids, β-cyclodextrin-modified capillary zone electrophoresis
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|