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KMID : 0043320160390060747
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Archives of Pharmacal Research
2016 Volume.39 No. 6 p.747 ~ p.754
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Chemical constituents from the fruiting bodies of Cryptoporus volvatus
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Wang Junchi
Li Guangzhi
Lv Na
Gao Li
Cao Li
Shen Liangang
Si Jianyong
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Abstract
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New drimane-type sesquiterpene cryptoporol A (1), cryptoporic acid derivative 6′-cryptoporic acid E methyl ester (2), and pseudouridine derivative cryptoporine A (3), as well as a known ergosterol 5α,8α-epidioxy-22E-ergosta-6,22-dien-3β-ol (4), were isolated from a 90 % alcohol extract of the fruiting bodies of Cryptoporus volvatus. The structures of these compounds were established by spectroscopic analysis and circular dichroism. 5α,8α-epidioxy-22E-ergosta-6,22-dien-3β-ol (4) exhibited antiviral activity against porcine reproductive and respiratory syndrome virus, and all compounds showed weak antioxidant activities.
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KEYWORD
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Cryptoporus volvatus, Sesquiterpene, Cryptoporic acid derivative, Pseudouridine derivative, Antiviral activity
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