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KMID : 0061119830110000174
Bulletin of the Clinical Research Institute
1983 Volume.11 No. 0 p.174 ~ p.174
Neuromuscular Effect of Succinylcholine During Halothane and Thalamonal Anesthesia
Suh Jae-Hyun

Whang Ho-Sik
Abstract
Thalamonal¢¥(Innovar) consisted of droperidol, a tranquilizer, and fentanyl, a short acting narcotic.
There was some reports of interaction of thalamonal on the depolarizing muscle relaxant.
This study was undertaken to quantify the neuromuscular effect of thalamonal compared with halothane anesthesia on succinylcholine induced neuromuscular blockade.
Forty non-pregnant women were randomly divided in halothane 1% (twenty) and thalamonal 0.5 §¢/10 §¸ (twenty) group, and their mechanical isometric adductor pollicis activity was monitored after bolus injection of succinylcholine 1 §·/§¸.
The onset time, time from onset of action to full paralysis, duration of full paralysis and recovery index were analyzed.
The results were as follows.
1. In halothane 1% group: the onset time was 16.0¡¾3.21 sec, time from onset to full paralysis was 48.4 ¡¾8.97 sec. Recovery index was 77.7¡¾19.26 sec.
2. In thalamonal 0.5 §¢/10 §¸ group: the time to onset of action was 16.7¡¾2.74 sec, time from onset to full paralysis was 43.2¡¾8.09 sec and duration of full paralysis was 347.7¡¾102.03 sec (p < 0.05). Recovery index was 93.3¡¾23.86 (p>0.05).
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