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KMID : 0191120040190060911
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Journal of Korean Medical Science
2004 Volume.19 No. 6 p.911 ~ p.914
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Metastatic Glioblastoma in Cervical Lymph Node after Repeated Craniotomies:Report of a Case with Diagnosis by Fine Needle Aspiration
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Moon KS
Jung S/Lee MC/Kim IY/Kim HW/Lee JK/Kim TS
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Abstract
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Head and neck metastasis from glioblastoma is rare event usually seen in patients with previous and repeated surgery. We present the case of a 35 yr-old-female suffering from metastatic glioblastoma in cervical lymph node that was diagnosed by fine needle aspiration. During the last 4 yr, she had four separate craniotomies for the recurrent brain tumors. Cytological diagnosis was made by light microscopy with immunostaining with glial fibrillay acid protein. Chemotherapy with vincristine and procarbazine was performed. The cervical masses were decreased in size and some disappeared while the intracranial glioblastoma continued to grow dur-ing chemotherapy. We discuss possible explanations for these different courses after chemotherapy in extraneural metastatic glioblastoma and primary intracranial glioblastoma.
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