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KMID : 0191120150300060802
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Journal of Korean Medical Science
2015 Volume.30 No. 6 p.802 ~ p.807
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Shock Duration after Resuscitation Is Associated with Occurrence of Post-Cardiac Arrest Acute Kidney Injury
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Kim Yong-Won
Cha Kyoung-Chul
Cha Yong-Sung
Kim Oh-Hyun
Jung Woo-Jin
Kim Tae-Hoon
Han Byoung-Keun
Kim Hyun
Lee Kang-Hyun
Choi Eun-Hee
Hwang Sung-Oh
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Abstract
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This retrospective observational study investigated the clinical course and predisposing factors of acute kidney injury (AKI) developed after cardiac arrest and resuscitation. Eighty-two patients aged over 18 yr who survived more than 24 hr after cardiac arrest were divided into AKI and non-AKI groups according to the diagnostic criteria of the Kidney Disease/Improving Global Outcomes (KDIGO) Clinical Practice Guidelines for AKI. Among 82 patients resuscitated from cardiac arrest, AKI was developed in 66 (80.5%) patients (AKI group) leaving 16 (19.5%) patients in the non-AKI group. Nineteen (28.8%) patients of the AKI group had stage 3 AKI and 7 (10.6%) patients received renal replacement therapy during admission. The duration of shock developed within 24 hr after resuscitation was shorter in the non-AKI group than in the AKI group (OR 1.02, 95% CI 1.01-1.04, P < 0.05). On Multiple logistic regression analysis, the only predisposing factor of post-cardiac arrest AKI was the duration of shock. In conclusion, occurrence and severity of post-cardiac arrest AKI is associated with the duration of shock after resuscitation. Renal replacement therapy is required for patients with severe degree (stage 3) post-cardiac arrest AKI.
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KEYWORD
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Cardiac Arrest, Resuscitation, Acute Kidney Injury, Renal Failure, Heart Arrest, Post-cardiac Arrest Syndrome, Renal Replacement Therapy
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