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KMID : 0191120170320071160
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Journal of Korean Medical Science
2017 Volume.32 No. 7 p.1160 ~ p.1165
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Comparison of Electroencephalography (EEG) Coherence between Major Depressive Disorder (MDD) without Comorbidity and MDD Comorbid with Internet Gaming Disorder
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Youh Joo-Hyung
Hong Ji-Sun
Han Doug-Hyun
Chung Un-Sun
Min Kyoung-Joon
Lee Young-Sik
Kim Sun-Mi
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Abstract
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Internet gaming disorder (IGD) has many comorbid psychiatric problems including major depressive disorder (MDD). In the present study, we compared the neurobiological differences between MDD without comorbidity (MDD-only) and MDD comorbid with IGD (MDD+IGD) by analyzing the quantitative electroencephalogram (QEEG) findings. We recruited 14 male MDD+IGD (mean age, 20.0 ± 5.9 years) and 15 male MDD-only (mean age, 20.3 ± 5.5 years) patients. The electroencephalography (EEG) coherences were measured using a 21-channel digital EEG system and computed to assess synchrony in the frequency ranges of alpha (7.5?12.5 Hz) and beta (12.5?35.0 Hz) between the following 12 electrode site pairs: inter-hemispheric (Fp1?Fp2, F7?F8, T3?T4, and P3?P4) and intra-hemispheric (F7?T3, F8?T4, C3?P3, C4?P4, T5?O1, T6?O2, P3?O1, and P4?O2) pairs. Differences in inter- and intra-hemispheric coherence values for the frequency bands between groups were analyzed using the independent t-test. Inter-hemispheric coherence value for the alpha band between Fp1?Fp2 electrodes was significantly lower in MDD+IGD than MDD-only patients. Intra-hemispheric coherence value for the alpha band between P3?O1 electrodes was higher in MDD+IGD than MDD-only patients. Intra-hemispheric coherence values for the beta band between F8?T4, T6?O2, and P4?O2 electrodes were higher in MDD+IGD than MDD-only patients. There appears to be an association between decreased inter-hemispheric connectivity in the frontal region and vulnerability to attention problems in the MDD+IGD group. Increased intra-hemisphere connectivity in the fronto-temporo-parieto-occipital areas may result from excessive online gaming.
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KEYWORD
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Internet Gaming Disorder, Major Depressive Disorder, Quantitative Electroencephalogram, Coherence
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