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KMID : 0213520180320020095
Korean Journal of Ophthalmology
2018 Volume.32 No. 2 p.95 ~ p.102
Lamina Cribrosa Changes after Laser In Situ Keratomileusis in Myopic Eyes
Lee Soo-Min

Choi Da-Ye
Lim Dong-Hui
Chung Tae-Young
Han Jong-Chul
Kee Chang-Won
Abstract
Purpose: To determine deep optic nerve head structure changes after transient intraocular pressure elevation during laser in situ keratomileusis (LASIK) for myopia.

Methods: Enhanced depth imaging-optical coherence tomography was performed in each myopic eye that underwent LASIK surgery. Enhanced depth imaging-optical coherence tomography images were created at postoperative 1 day, 1 week, 2 weeks, and 1 month. Lamina cribrosa (LC) thickness, LC depth and prelaminar thickness at the superior, middle and inferior portions of the optic nerve head were measured by two investigators.

Results: Forty eyes in 40 patients were included in the present study. During follow-up, there were no significant differences in prelaminar thickness or LC depth. The LC demonstrated increased thickness at postoperative 1 day at all three locations (superior, middle, and inferior) (p < 0.001, p < 0.001, p < 0.001, respectively). However, no significant changes were observed at postoperative 1 week, 2 weeks, and 1 month.

Conclusions; The LC thickness could increase at 1 day after LASIK surgery. However, the thickness will gradually return to baseline morphology. Temporary intraocular pressure increase during LASIK does not appear to induce irreversible LC thickness changes.
KEYWORD
Lamina cribrosa, Laser in situ keratomileusis, Optic disk
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