KMID : 0355620100360060508
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Journal of Korean Association of Oral and Maxillofacial Surgeons 2010 Volume.36 No. 6 p.508 ~ p.514
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Clinical feature and treatment of bisphosphonate-related osteonecrosis of jaw about oral bisphosphonate administrated patients: case reports
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Choi Woo-Sung
Yoon Hyun-Joong Lee Sang-Hwa
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Abstract
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Bisphosphonates are used effectively for many medical conditions, such as multiple myeloma, Paget¡¯s disease, osteoporosis, etc. However, recently, osteonecrosis of the jaw was observed in patients receiving long-term bisphosphonate therapy, including oral administration. This osteonecrosis is refractory, and complete recovery is not guaranteed despite a standard treatment protocol being established by many associations related to oral and maxillofacial surgery. The treatment outcome of oral bisphosphonate-related osteonecrosis of jaw (BRONJ) is reported with a review of the relevant literature
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KEYWORD
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Bisphosphonate, Osteonecrosis, Osteoporosis
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