KMID : 0356820120280010037
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Korean Journal of Head & Neck Oncology 2012 Volume.28 No. 1 p.37 ~ p.41
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A Case of Malignant Peripheral Nerve Sheath Tumor with Hypopharyngeal Cancer
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Lim Sang-Ho
Lee Kyung-Suk Yang Yun-Su Hong Ki-Hwan
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Abstract
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The malignant peripheral nerve sheath tumor(MPNST) is an extremely rare soft tissue sarcoma of ectomesenchyme also known as malignant schwannoma or malignant neurilemoma. It is a highly malignant sarcoma, which is locally invasive, frequently leading to multiple recurrences and eventual metastatic spread. The peak incidence of this disease is known to arise in the seventh decades. In human body, trunk and extremities are the most commonly involved sites, and only 8-14% of all lesions appear in head and neck region. Because immunohistochemical staining is essential in final diagnosis. The authors report a case of malignant peripheral nerve sheath tumor in neck with hypopharyngeal cancer simultaneously on a review of the literature.
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KEYWORD
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Malignant peripheral nerve sheath tumor(MPNST), Hypopharyngeal cancer
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