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KMID : 0359319950350010055
Korean Journal of Veterinary Research
1995 Volume.35 No. 1 p.55 ~ p.65
Electron microscopic study on the insulin - , glucagon - , somatostatin - , and pancreatic polypeptide secreting cells in Korean native goat





Abstract
Ultrastructures of pancreatic endocrine cells containing glucagon, insulin, somatosratin and pancreatic polypeptide were studied in the pancreas of the Korean native goat by immunohistochemical and elecron microscopy.
Glucagon immunoreatctive cells were round or fusiform in shape and contained secretory granules of 200-260 §¬ in diameter. The secretory granules were high in electron density and had a halo between the limiting membrane and the central granule core. Insulin immunoreactive cells were round or oval in shape, and contained various sizes of secretory granules from 135 to 300 §¬ in diameter. The secretory granules were low or moderate electron density and had a variform halo. Somatostatin immunoreactive cells were elliptical or fusiform shape with cytoplasmic processes. They contained the secretory granules of 140-320 §¬ with moderate electron densities. Pancreatic polypeptide immunoreactive cells were elliptical or fusiform and contained small secretory granules with high electron densities. The secretory granules were 120-230 nm in diameter and the least in number.
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