KMID : 0360220120530101425
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Journal of the Korean Ophthalmological Society 2012 Volume.53 No. 10 p.1425 ~ p.1431
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Long Term Clinical Results of Penetrating Keratoplasty for Macular Corneal Dystrophy
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Lee Ji-Myung
Hwang Kyu-Yeon Hwang Ho-Sik Kim Man-Soo
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Abstract
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Purpose: To report the long term clinical results of penetrating keratoplasty as a treatment for corneal macular dystrophy.
Methods: Retrospective review of the medical record of 46 eyes (31 indivisuals) who underwent primary PK for corneal macular dystrophy at the Seoul St. Mary¡¯s Hospital between November, 1986 and December, 2011. Data extracted preoperative and postoperative best-corrected visual acuity (BCVA), postoperative complications (including graft rejection episodes, and recurrent dystrophy), change of endothelial cell density at 1, 6, 12, 24, 36 months and yearly thereafter.
Results: After a mean follow-up period of 91.59 ¡¾ 3.2 months, the mean BCVA was significantly improved after penetrating keratoplasty. Endothelial cell loss rate was marked during the 1st year after penetrating keratoplasty. Graft survival was 40 graft (89.7%) at 8yrs. There was a statistically significant increased likelihood of graft failure if the patient was older than 40 years at the time of surgery (p = 0.03). Glaucoma as postoperative complication was 17.4%. Clinically significant recurrence was 2%.
Conclusions: Penetrating keratoplasty is associated with a good visual outcome and prognosis for graft survival of long-term efficacy with a low complication rate in eyes with macular corneal dystrophy.
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KEYWORD
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Corneal macular dystrophy, Penetrating keratoplasty
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