KMID : 0361020230660070480
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Korean Journal of Otolaryngology - Head and Neck Surgery 2023 Volume.66 No. 7 p.480 ~ p.484
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Nasopharyngeal DLBCL Misdiagnosed as a Nasal Polyp in an 84-Year-Old Patient: A Case Report
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Bang Je-Ho
Lee Jong-Hwan Son Seung-Yup Lee Kun-Hee
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Abstract
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Malignant lymphoma is a malignant tumor that occurs in the lymphocytes but can also occuranywhere in the body. On the other hand, malignant lymphomas originating from the naso-pharyngeal space are very rare. We experienced a case of 84-year-old female patient with ahuge nasopharyngeal mass, who had no complaints other than right nasal congestion, inter-mittent rhinorrhea, and sneezing. A physical examination revealed a large, polypoid, transpar-ent mass at her right nasal cavity. Nasal polyp was suspected and endoscopic sinus surgerywas performed. On histological examination, she was diagnosed with diffuse large B celllymphoma, with CD20, BCL-2, and BCL-6 positive. Low dose maintenance chemotherapywas carried out in consideration of the patient¡¯s age. A complete remission is expected basedon the imaging tests following chemotherapy. We report a huge malignant lymphoma that oc-curred in an elderly patient¡¯s nasopharyngeal space and successful low dose chemotherapywith a review of literature.
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KEYWORD
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Diffuse large B cell lymphoma, Lymphoma, Maintenance chemotherapy, Nasopharynx neoplasm
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