Idiopathic CD4+ T lymphocytopenia(ICL) is a new disease entity characterized by depletion of helper T cells apparently without any evidence of HIV infection.
We report a case of ICL associated with kaposi's sarcoma(KS) and pneumocystis carinii pneumonia(PCP) in a 34-year-old woman. She developed violaceous, protruding masses on scalp. Back, both extremities, palms. Soles, left first toe and
peritonsillar
region for 2 months. These lesions were confirmed as KS by histopathologic findings. Chest X-ray and HRCT findings represented PCP and KS. Absolute deficiency of CD4+ T cell was detected in the count of T cell subsets. Serologic tests for HIV-1,
-2
and
HTLV-I, _II were negative. And she was absent any defined immunodeficiency or therapy associated with decreased levels of CD4+ T cells. By CDC criteria, a diagnosis of ICL was made. Because of aggravation of PCP and lung involvement of KS, she
died
at
22nd day after admission. (Kor J Dermatol 1997;35(1) : 191∼195)
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