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KMID : 0363220130510020144
Korean Journal of Dermatology
2013 Volume.51 No. 2 p.144 ~ p.147
A Case of Diffuse Dermal Angiomatosis
Min Joon-Hong

Seo Hyun-Min
Lee Hyun-Joo
Park Ji-Hye
Choi Chong-Won
Lee Ga-Young
Kim Won-Serk
Abstract
Diffuse dermal angiomatosis is an acquired, benign vascular proliferation with poorly circumscribed, violaceous, and livedoid plaques with frequent ulceration. Histologically, there is diffuse and interstitial proliferation of CD31- positive endothelial cells and myofibroblasts within the dermis. Endothelial atypia, mitoses, and vasculitis are lacking. Here we describe a 52-year-old male who presented with erythematous and purpuric patches on the trunk and lower extremities for 2 years. Histologic examination demonstrated a dense proliferation of endothelial cells in the papillary and reticular dermis. Small vascular spaces and extravasated erythrocytes were noted. Immunohistochemical staining using anti-CD31 antibody was positive.
KEYWORD
CD31, Diffuse dermal angiomatosis, Reactive angioendotheliomatosis
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