KMID : 0363220130510020144
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Korean Journal of Dermatology 2013 Volume.51 No. 2 p.144 ~ p.147
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A Case of Diffuse Dermal Angiomatosis
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Min Joon-Hong
Seo Hyun-Min Lee Hyun-Joo Park Ji-Hye Choi Chong-Won Lee Ga-Young Kim Won-Serk
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Abstract
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Diffuse dermal angiomatosis is an acquired, benign vascular proliferation with poorly circumscribed, violaceous, and livedoid plaques with frequent ulceration. Histologically, there is diffuse and interstitial proliferation of CD31- positive endothelial cells and myofibroblasts within the dermis. Endothelial atypia, mitoses, and vasculitis are lacking. Here we describe a 52-year-old male who presented with erythematous and purpuric patches on the trunk and lower extremities for 2 years. Histologic examination demonstrated a dense proliferation of endothelial cells in the papillary and reticular dermis. Small vascular spaces and extravasated erythrocytes were noted. Immunohistochemical staining using anti-CD31 antibody was positive.
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KEYWORD
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CD31, Diffuse dermal angiomatosis, Reactive angioendotheliomatosis
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