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KMID : 0363220170550040249
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Korean Journal of Dermatology
2017 Volume.55 No. 4 p.249 ~ p.252
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Multiple Giant Keratoacanthoma Treated with Acitretin
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Kwon Eun-Sun
Lee Kyoung-Geun
Koh Byoung-Yong
Myung Ki-Bum
Cheong Seung-Hyun
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Abstract
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Giant keratoacanthoma is an uncommon variant of keratoacanthoma, which may increase to a diameter of several centimeters. Although keratoacanthomas usually resolve spontaneously, giant keratoacanthoma can be invasive and destructive. A 49-year-old man presented with a 5-year history of multiple large hyperkeratotic and crusted plaques and nodules on sun-exposed areas such as the face, ear, hand, and forearm. Some lesions involuted spontaneously, whereas others became rather enlarged. The biopsy specimen revealed horn-filled crater formation, epidermal extending resembling a buttress, and an eosinophilic glassy appearance in the keratinocytic cytoplasm. We treated the lesions with acitretin, and they almost completely resolved after 13 weeks. Here we describe a case of multiple giant keratoacanthoma treated with acitretin.
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KEYWORD
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Acitretin, Giant keratoacanthoma, Keratoacanthoma
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