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KMID : 0363220210590020132
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Korean Journal of Dermatology
2021 Volume.59 No. 2 p.132 ~ p.135
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A Case of Hand-Foot-Mouth Disease Caused by Coxsackievirus A6
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Kim Ho-Young
Uh Ji-An
Kim Joong-Ho
Lee Jae-Ho
Lee Soo-Kyung
Kim Myoung-Shin
Lee Un-Ha
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Abstract
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Hand-foot-mouth disease (HFMD) is a viral infection that occurs commonly in children. It is characterized by vesicles with surrounding erythema on the extremities and mouth. Most common pathogens are Coxsackievirus A16 and Enterovirus 71. HFMD caused by Coxsackievirus A6 is uncommon and accompanied by more extensive and atypical eruptions. A 42-year-old man presented with erythematous papules and vesicles on the right hand which occurred 7 days prior to presentation. The rash spread extensively with high fever, chills, headache, and myalgia. He also had whitish ulcer-like lesions on the oral mucosa with swallowing difficulty. One day after hospitalization, he developed arthralgia on his shoulders, pelvis, knees, and fingers. The biopsy specimen showed an intraepidermal blister with reticular degeneration, epidermal necrosis, and neutrophilic infiltration. There were no inclusion cells or giant cells. The serum antibody titer of Coxsackievirus A6 showed a significant increase, at 64 times. He was diagnosed with HFMD caused by Coxsackievirus A6.
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KEYWORD
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Coxsackievirus infections, Enterovirus infections, Hand-foot-mouth disease
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