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KMID : 0363220210590030188
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Korean Journal of Dermatology
2021 Volume.59 No. 3 p.188 ~ p.195
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Chondroid Syringoma: A Clinical and Histopathological Study of 17 Cases
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Lee Seon-Bok
Yeom Seung-Dohn
Shin Jeong-Hyun
Choi Gwang-Seong
Byun Ji-Won
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Abstract
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Background: Chondroid syringoma (CS) is an uncommon benign neoplasm of the head and neck seen in middle-aged to elderly individuals. Histopathologically, chondroid syringoma displays nests of cuboidal epithelial cells embedded in a matrix. It is classified as both a tubular branching lumina type and a small tubular lumina type and may exhibit a wide range of differentiation and metaplastic changes in the epithelial and stromal components.
Objective: To investigate the correlation between the clinical and histopathologic features of chondroid syringoma.
Methods: We evaluated the electronic medical records, clinical photographs, and histopathological slides of 17 patients diagnosed with chondroid syringoma.
Results: CS in the terminal hair skin tended to have larger lesions (p=0.036). Tumors in terminal hair skin demonstrated significantly more follicular differentiation (p=0.044) than those in the vellus hair skin. CS arising on the scalp tended to have more osseous metaplasia compared to those arising on non-scalp areas (p=0.022).
Conclusion: This study showed that the clinical and histopathological features of CS can differ depending on its location.
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KEYWORD
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Chondroid syringoma, Clinical, Histopathologic
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