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KMID : 0363220220600090566
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Korean Journal of Dermatology
2022 Volume.60 No. 9 p.566 ~ p.575
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Clinicopathological Study of Urticarial Vasculitis: A Single-Center Study with Sixty-Five Patients in Korea
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Kim Ji-Sun
Koo Dae-Won
Lee Joong-Sun
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Abstract
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Background: Urticarial vasculitis (UV) is a rare disorder that can be diagnosed with clinical and histopathologicstudies. There are classical clinical criteria; however, histopathological evidence is required for a definite diagnosis.
Few studies have reported on the clinical and histological features of UV.
Objective: To analyze the clinical and histopathologic features of patients diagnosed with UV at a single center inthe Republic of Korea.
Methods: We performed a retrospective study of the medical records, clinical photographs, and histopathologicalslides of patients who visited the Department of Dermatology at Daejeon Eulji Medical Center for urticarial whealsor purpuric plaques lasting more than 24 hours from January 2013 to October 2021.
Results: A total of 65 patients and 95 slides were analyzed. Clinically, most patients had wheal-like plaquedominant lesions (55 patients, 84.6%) rather than purpura and presented with pruritus. In the histopathological study,lymphocytic vasculitis (65 of 69 slides, 94.2%) was more dominant than leukocytoclastic vasculitis. However, itsseverity was milder than that of leukocytoclastic vasculitis.
Conclusion: This study performed a more in-depth clinical and histological analysis of UV, and histologically, itshowed more diversity than previously known leukocytoclastic vasculitis. This might be used as basic research datafor more large-scale studies of UV in the future.
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KEYWORD
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Leukocytoclastic vasculitis, Lymphocytic vasculitis, Urticarial vasculitis
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