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KMID : 0363220230610070443
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Korean Journal of Dermatology
2023 Volume.61 No. 7 p.443 ~ p.446
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Bullous Pilomatricoma Arising at a BNT162b2 mRNA COVID-19 Vaccination Site
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Kim Kyu-Yeon
Choi Young-Jun
Lee Ga-Young
Kim Won-Serk
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Abstract
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Pilomatricoma is a common benign tumor that originates from hair matrix cells. Bullous pilomatricoma (BP) is a rare variant that often occurs on the upper extremities. A 23-year-old male presented with a cyst on the left upper arm for 6 months. He received the BNT162b2 (Pfizer) mRNA COVID-19 vaccine in the same location approximately 6 months prior to presentation. The lesion appeared 1 week after inoculation and gradually enlarged.
Physical examination revealed a 2.5-×2.0-cm-sized, pinkish cystic nodule on the left upper arm. The lesion was excised, and histopathological examination showed a well-circumscribed nodule composed of basophilic cells and eosinophilic shadow cells. Finally, the patient was diagnosed with BP. The exact cause of BP formation following vaccination is yet to be determined; however, this report presents the possibility of BP occurrence in individuals with chronic skin lesions at the site of vaccination.
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KEYWORD
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COVID-19, Pilomatrixoma, Skin neoplasm
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