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KMID : 0363420220360030075
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Journal of Korean Oriental Pediatrics
2022 Volume.36 No. 3 p.75 ~ p.86
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Review of Recent Clinical Research for Oral Herbal Medicine Treatment on Primary Hyperhidrosis in Children - Focused on Chinese Randomized Controlled Trials -
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Choi Il-Shin
Kim Ki-Bong
Cheon Jin-Hong
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Abstract
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Objectives : The purpose of the study is to review the trend of clinical trials conducted in China with oral herbal medicine
treatment on childhood primary hyperhidrosis.
Methods : We searched the randomized controlled trials (RCTs) with oral herbal medicine treatment on childhood primary
hyperhidrosis from the China National Knowledge Infrastructure (CNKI). The demographic data, duration of illness,
intervention, treatment period, outcome and composition of herbal medicine were analyzed for this study.
Results : A total of five RCTs were selected and analyzed. The effectiveness of the oral administration of herbal medicines
on childhood primary hyperhidrosis was found to be significant. In one study, there was no statistical difference
between the treatment group and the control group when curative effect was evaluated two weeks after the
intervention; however, the treatment group showed a statistically higher curative effect than the control group at
one and two months after intervention, and also one month after the intervention was terminated.
Conclusions : Oral herbal medicine has been shown to be an effective treatment for childhood primary hyperhidrosis, and it takes at least one month for the administered oral herbal medicines to take effect. However, further well-designed
large-scale randomized controlled trials are needed to confirm the efficacy and safety of oral herbal medicines in
childhood primary hyperhidrosis.
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KEYWORD
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Childhood primary hyperhidrosis, Randomized controlled trials, Oral herbal medicine, Review
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