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KMID : 0363720090420020115
Korean Journal of Anatomy
2009 Volume.42 No. 2 p.115 ~ p.122
Immunohistochemical Analysis of Calretinin and Parvalbumin in the Goat Main Olfactory Bulb
Choi Jung-Hoon

Shin Hyung-Cheul
Won Moo-Ho
Lee In-Se
Yoon Yeo-Sung
Hwang In-Koo
Yoo Ki-Yeon
Lee Choong-Hyun
Abstract
The distributions of calretinin (CR)- and parvalbumin (PV)-immunoreactive neurons in the main olfactory bulb (MOB) of the goat were examined in this study. As in other animals, the goat MOB has a characteristic laminar structure with laminar types and distribution patterns in each layer. CR-immunoreaction was observed in all layers of the MOB, except for the olfactory nerve layer. Most of CR-immunoreactive neurons were observed in the glomerular and granule cell layers. Relatively small number of CR-immunoreactive neurons was detected in other layers. These CR-immunoreactive neurons were interneurons. PV-immunoreaction was detected in all layers. In contrast to CR, olfactory nerve bundles were immunostained with PV. Most of PV-immunoreactive neurons were distributed in the glomerular and granule cell layers. PV-immunoreactive neurons were interneurons. This result suggests that CR and PV may play important roles in the olfactory signal modulation through interneurons in the goat MOB.
KEYWORD
Calcium-binding proteins, Goat, Immunohistochemistry, Olfaction, Olfactory bulb
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