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KMID : 0364819860240030221
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Korean Journal of Microbiology
1986 Volume.24 No. 3 p.221 ~ p.227
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The Effects of uvsH Gene in Aspergillus nidulans on Mitotic Recombination Behabiour
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Chae, Suhn Kee/채순기
Han, Dong Min/Kang, Hyen Sam/한동민/강현삼
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Abstract
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1
The strain of Aspergillus nidulans tarring a uvsH mutation which had been shown to be absolutely required for UV or 4- NQO induced mutagenic processes was studied on mitotic recombinational behaviour. Although the effect of uvsH locus on spontaneous mitotic crossing over between fpB37 and centromere was not considerable, UV-induced intergenic recombination did not occur in uvsH/uvsH homozygotic diploid. In case of gene conversion at riboflavin locus between a pair of non-complementary alleles, riboAl and riboA3, the uvsH mutation was not concerned with that process occurred spontaneously or induced by UV irradiation. When the cells were irradiated by UV light, high degrees of aneuploid productions were detected in diploid homozygous for uvsH as compared with wild type, while much difference was not found during normal growth.
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