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KMID : 0364820100460020200
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Korean Journal of Microbiology
2010 Volume.46 No. 2 p.200 ~ p.206
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Antibacterial Effect of Oriental Medicinal Herbs on Dental Pathogens
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Yu Young-Eun
Park Eun-Young
Jung Dae-Hwa
Byun Sung-Hui
Kim Sang-Chan
Park Sung-Min
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Abstract
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In this study, we investigated the antibacterial effect of 69 oriental medicinal herbs (OMHs) on Actinomyces viscocus, Streptococcus sobrinus, and two strains of Streptococcus mutans as oral bacteria. Methanol extracts of OMHs were used in the first antibacterial test, and then boiled water, ethanol, methanol, and ethyl acetate extracts of C. japonica, C. sappan, P. mume, and S. chinensis were used in the second test. Boiled water extract of C. japonica was shown to have the most superior effect on oral bacteria. The extract yield of boiled water extract of C. japonica was 22%, and the growth of oral bacteria was almost inhibited at over a 180 mg/ml concentration. Antibacterial effect compound analyzed by UPLC method was identified as berberine, and the content was 25.54%. In addition, the extract appeared to be stable at 121°C for 15 min.
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KEYWORD
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antibacterial effect, dental pathogen, oriental medicinal herb
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