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KMID : 0364820100460030229
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Korean Journal of Microbiology
2010 Volume.46 No. 3 p.229 ~ p.232
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Studies on the Functional Role of RNase G in the Regulation of Escherichia coli Enolase Expression Under Microaerobic Conditions
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Sim Se-Hoon
Kim Yong-Hak
Sim Min-Ji
Lim Bo-Ram
Lee Kang-Seok
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Abstract
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Enolase is one of the glycolytic enzymes, which are involved in a central energy metabolism present in nearly all organisms. In Escherichia coli, enolase constitutes RNA degradosome with RNase E, PNPase and RNA helicase, which are involved in most mRNA degradation and RNA processing. Recently, it has been reported that RNase G, an RNase E homolog, degrades eno mRNA. To examine a functional role of RNase G in enolase expression which is known to be up-regulated under microaerobic condition, we carried out experiments. Here, we report that expression levels of enolase and RNase G are not correlated under microaerobic condition. Based on this observation, we suggest the existence
of an unknown factor(s) which regulate the activity of RNase G or enolase mRNA under microaerobic conditions.
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KEYWORD
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enolase, microaerobic, RNA degradosome, RNA regulation, RNase G
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