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KMID : 0368820150540040564
Journal of the Korean Neuropsychiatr Association
2015 Volume.54 No. 4 p.564 ~ p.569
Comparison of Neurocognitive Functions between Positional Obstructive Sleep Apnea Patients and Non-Positional Obstructive Sleep Apnea Patients in the Korean Elderly Population
±èÇüÂù:Kim Hyung-Chan
°­¼®ÈÆ:Kang Suk-Hoon/ÃÖÁøÈñ:Choi Jin-Hee/Á¤Çý°æ:Chung Hae-Gyung/±èÅ¿ë:Kim Tae-Yong/¼ÒÇü¼®:So Hyung-Seok
Abstract
Objectives: Obstructive sleep apnea (OSA) is classified as positional sleep apnea (POSA) and non-positional sleep apnea (NPOSA) according to apnea-hypopnea index (AHI) changed by sleep position. The aim of this study was to compare neurocognitive functions between two groups in the elderly Korean population.

Methods: Forty-four subjects in OSA patients with total AHI¡Ã5 participated as criteria for POSA (n=25) with 1) supine position AHI/non-supine position AHI¡Ã2 and 2) total AHI¡Ã5 or not (NPOSA, n=19). All participants completed clinical interview by physician and neurocognitive function assessments. Mann-Whitney U and chi-square test were performed for comparison of neurocognitive functions and sleep characteristics with polysomnography between two groups.

Results: No significant difference in demographic and clinical characteristics was observed between the two groups. However the NPOSA group showed more decline than the POSA group on the Boston naming test (p=0.034), digit span test (p=0.001), go-no-go test (p=0.042), and fist-edge-palm test (p=0.007).

Conclusion: In this study NPOSA patients were found to have lower cognitive functions compared to POSA patients. A larger sample and long term follow-up study might be needed.
KEYWORD
Obstructive sleep apnea, Sleep position, Non-positional sleep apnea, Polysomnography, Neurocognitive function
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