Postoperative brain damage is one of most serious complications of cardiopulmonary bypass (CPB). To prevent brain damage during CPB, adequate cerebral perfusion for cerebral oxygen demand should be maintained. This study monitored jugular venous
oxyhemoglobin saturation (SjO2), which reflects the overall balance of cerebral oxygen supply and demand, intermittently in 10 patients undergoing cardiac surgery.
At the initiation of CPB, in spite of a significant decrease in mean arterial pressure, SjO2 did not change, and it was stable during the hypothermic period of CPB. But a significan reduction in SjO2 was observed during the rewarming period, and
SjO2
had an inverse linear correlation with esophageal temperature. Furthermore, the percent decrease of SjO2 was related to rewarming speed.
Therefore, therapeutic approaches for SjO2 desaturation include slower rewarming, increasing cerebral blood flow, decreasing the cerebral metabolic rate for oxygen, increasing oxygen content, and increasing perfusion flow rate.
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