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KMID : 0370920100270010078
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Yeungnam Univercity Journal of Medicine
2010 Volume.27 No. 1 p.78 ~ p.84
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A Case of Systemic Lupus Erythematosus Misdiagnosed as Adult-onset Still’s Disease
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Oh Myung-Jin
Hong Young-Hoon
Lee Choong-Ki
Hur Ji-An
Kim Hyun-Je
Lee Han-Sol
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Abstract
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Adult-onset Still’s disease (AOSD) is an inflammatory disorder that’s characterized by daily, spiking high fever, arthritis and an evanescent, salmon-pink rash. AOSD is diagnosed purely on the basis of the typical clinical features of the illness. The symptoms commonly include swelling of the lymph nodes, enlargement of the spleen and liver, and a sore throat. AOSD is difficult to differentiate from systemic lupus erythematosus (SLE) due to the similar clinical manifestations. We report here on a case of a 16-year-old female patient with autism and epilepsy and who complained of daily spiking fever for 20 days. The patient had maculopapular skin rashes on the face and whole body and lymphadenopathy. The liver function tests were elevated mildly. The initial rheumatoid factor (RF) and antinuclear antibody (ANA) tests were negative. We diagnosed her as having adult-onset Still’s disease according to the criteria of Yamaguchi. We successfully treated her with oral prednisolone. But her antinuclear antibody test was changed to positive after discharge. So we finally diagnosed her as having SLE.
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KEYWORD
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Adult-onset Still’s disease, Systemic lupus erythematosus, Antinuclear antibody
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