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KMID : 0371019970300010017
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Journal of Preventive Medicine and Public Health
1997 Volume.30 No. 1 p.17 ~ p.30
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Seroepidemiologic Study of Hepatitis B Virus (HBV) and Hepatitis C Vir (HCV) Infection among Koreans in Rural Area, Korea
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Shin Hai-Rim
Kim Jun-Youn
Song Jue-Bok
Suh Byung-Seong
Kim Jung-Man
Rhee Boo-Ouk
Kimn Su-Ryang
Ryang Mu-Guan
Lee Chae-Un
Chun Jin-Ho
Yoo Keun-Young
Ahn Yoon-Ok
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Abstract
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To estimate the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection and to determine associated risk factors, a population-based seroepidemiologic study was carried out. In 1993, a health examination survey of the population was carried out in rural area known to have a high incidence of liver cancer. The study population were those who volunteered to participate in a health survey over 10 years of age. Examinees were interviewed by specially trained staffs. Sera from 1,033 study subjects were tested for hepatitis B surface antigen (HBsAg) by reverse passive hemagglutinin (RPHA) estimation and for hepatitis C virus antibody (anti-HCV) by 2nd generation passive hemagglutinin (PHA) estimation. The age and sex standardized prevalence of HBsAg was 6.3% which was similar to national average, but that of anti-HCV was 5.1 % which was 4 to 5 times higher than that of Mood donors or other health examinees in Korea. In a multivariate analysis, transfusion; history, surgical operative history, and acupuncture history were not associated with HBsAg positivity. In contrast, acupuncture history (adjusted odds ratio[OR]=2.2 : 9~ % Confidence interval[CIJ 1.0-4.7) and surgical operative history(adjusted OR=2.0 : 95% CI 1.0-4.1) were associated with anti-HCV positivity. The present study suggest that there is an highly endemic area of HCV infection in Korea and probably this endemicity is associated with a parenteral source of HCV infection other than blood transfusion.
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KEYWORD
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Hepatitis B virus infection, Hepatitis C virus infection, Prevalence, Risk factors
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