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KMID : 0371219930150010112
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Medical Bulletin of the Presbyterian Medical Center
1993 Volume.15 No. 1 p.112 ~ p.120
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A Comparative Study o BUdR, AgNOR's, and PCNA in Begin and Malignant Astrocytoma
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이원창
신문수/정남/허승곤/이혜경
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Abstract
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In 14 cases of astocytoma, we performed a comparative study of BUdR, AgNOR's and PCNA with histopathology. Fourteen astrocytomas were classified histopathologically into low grade, anaplastic, and G. M. (glioblasoma multiforme) groups. These
comprised 3
G.M, 5 anaplastic astrocytomas, and 6 low grade astrocytomas.
The mean BUdR-LI(Labeling Index) was statistically different(P<0.005) between G. M. (10.4), anaplastic astrocytoma(3.6), and low grade astrocytoma(1.3). On the basis of correlation between BUdR-LI and histopathology, which was reported in 1989 at
PMC,
we examined the relationship between BUdR-LI and AgNOR's count, and between BUdR-LI and PCNA-LI, both AgNOR's count and PCNA-LI did not correlate with BUdR-LI, and also not with histopathology.
This study indicates that, at presents, for prognosis and differentiation between malign ant and benign astrocytoma, histopathology and BUdR-LI are important.
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KEYWORD
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