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KMID : 0374919930140020215
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Inje Medical Journal
1993 Volume.14 No. 2 p.215 ~ p.222
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A Study of Clinical Characteristics of Reflux Nephropathy and Effects of therapeutic Modalities
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Abstract
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At the Seoul Paik Hospital of Inje University during the 6 year period 1986 through 1992, reflux nephropathy was diagnosed in 35 patients. We have studied clinical characteristics of patients with reflux nephropathy and effects of therapeutic
modalities
on it.
1. The incidence of vesicoureteral reflux among patients less than 1 year of age was 3 times grater in boys than girls but 1.6 times more often in girls after 1 year of age.
2. Urinary tract infection was the most common cause for the evaluation of urinary tract by radiology, which accounted for 71.4%. Asymptomatic proteinuria was 14.3%. Other reasons included enuresis, growth retardation and CRF, fever of unknown
origin,
prenatal hydronephrosis and nephrotic syndrome with renal insufficiency.
3. E. coli was the most frequent organism isolated from patients with vesicoureteral reflux and urinary tract infection, which accounted fro 80%.
4. 85% of refluxed kidneys have already had renal scar on diagnosis and 13.2% of kidneys with scarring showed no reflux.
5. The severity of renal scar seemed to be related with the degree of vesicoureteral reflux.
6. 6 patients(17%) among total 35 patients progressed to chronic renal failure and their prominent clinical feature was massive proteinuria.
7. There was no significant differance between chemoprophylaxis group and operation group in terms of recurrance of urinary tract infection. It was 41% and 37.5% respectively.
8. 2(16.7%) of 12 patients who were on chemoprophylaxis showed no reflux in one to four period.
9. Reflux was abolished in 10(90.9%) among 11 patients who underwent ureters reimplanted. There were no severe complications after operation. Degree of reflux improved from grade III to grade I in remaining 1 patient.
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KEYWORD
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