We had following results through a clinical study of 285 women, who were admitted with a diagnosis of acute pyelonephritis proven by urine culture, to Pak Hospital, Sangge, Seoul from August 1989 to November 1994.
1) The distribution of the age incidence : 2nd decade(1.7%, over the age of 15), 3rd decade(19.6%), 4th decade(20.3%), 5th decade(8.0%), 6th decade(17.5%), over the age of 60(31.8%).
2) Distribution of the underlying diseases of the all subjects : diabetes(24.9%) hypertension(14.7%), urinary tract obstruction(9.1%), unknown(55%).
3) In the urine culture, most common microorganism was E. coli(89%), and next, Klebsiella pneumoniae(3.5%), Pseudomonas aeruginosa(2.1%), Staphylococcus aureus(1.4%), Enterococcus feacalis(1.1%), Proteus mirabilis(0.7%) in order of incidence.
Except
for abovementioned microorganisms there were single cases of Morganella morganii, Serratia marscecens, Streptococcus viridans, Providencia rettgeri and Bacillus species.
4) Distribution of the underlying diseases of 57 patients, who had E. coli. bacteremia : elderly(50.8%, over the age of 60), diabetes(42.1%), hypertension(24.5%), pregnancy(5.2%), unknown(22.8%).
5) In vitro sensitivity test of E. coli to antibiotics: ① ampicillin(13%), gentamicin(75%), amikacin(88%), Tobramycin(83%), cephalothin(52%), trimethoprim-sulfamethoxazole(49.8%) based on 255 tests. ② ciprofloxacin(95%) based on 70 tests.
③cefotaxim(98%) based on 69 tests.
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