|
KMID : 0377619640070050595
|
|
Korean Jungang Medical Journal
1964 Volume.7 No. 5 p.595 ~ p.601
|
|
|
Studies on the movement of Staphylococcal phage introduced into rabbit body by various methods
|
|
|
|
|
Abstract
|
|
|
The anthor has studied on the movement and condition of Staphylococcal phage introduced into rabbit body by various methods and obtained the following results.
The phage particles introduced into peritoneal cavity of rabbit were recovered from blood and, according to the progressing of time, the phage has gradually disappeared from blood, At this time, if phages were introduced into peritoneal cavity of the rabbit blocked previously all the Reticuloendothelial System and the phage for introducing into peritoneal cavity was diluted with distilled water, physiologic normal saline and normal saline plus 10-3M magnesium solution, no any special finding was observed during movement of the phage form peritoneal cavity to blood.
After inoculation of phage particles into peritoneal cavity of rabbit, more phages were recovered from the liver and spleen for the longest time, much phage particles have moved into urine and the phage was also demonstrated in stool.
The phage particles administered orally into rabbit body were recovreed from blood and stool.
The phage particles can pass through the placental barrier of rabbit and the phage injected into the ear vein of pregnant rabbit was recovered from the fetus.
In subcutaneous tissue spare of rabbit, the phage particles can not be freely moved out and, according to the progressing of time, the phage was easily inactivated.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|