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KMID : 0377619750280020166
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Korean Jungang Medical Journal
1975 Volume.28 No. 2 p.166 ~ p.174
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A Clinical Study on Renal Failure in Patients with Liver Diseases (Ⅰ)
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宋康子/Song, Kang Jeong
金悅子/李鍾錫/李學重/Kim, Yul Ja/Rhee, Chong Suk/Lee, Hak Choong
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Abstract
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Hundred forty cases of chronic liver diseases were collected to see the interrelationship between various clinical aspects of liver diseases and their renal functions.
The collected cases were consisted of 85 liver cirrhosis, 32 primary hepatoma and 23 chronic hepatitis which had been admitted to National Medical Center in Korea during the past 2 years. Data were analysed from the standpoint of BUN, serum creatinine and urinary amount in relation to various liver function tests and abdominal circumference in the presence of ascites, and the following results were obtained.
1) In the presence of ascites, the mean BUN level in cirrhosis was 20. 0±7. 24mg % and in hepatoma 27.9±9.39mg%. In the absence of ascites, the mean BUN level in cirrhosis was 15.7±6. 16mg%, in hepatoma 14.5+6.08mg% and in chronic hepatitis 15. 6±7. 01mg.
This data denoted relatively high BUN levels in the presence of ascites in respective liver disease entity.
2) In the presence of ascites, the mean serum creatinine level in cirrhosis was 1. 59±0. 42 mg% and in hepatoma 1.79±0.47mg%. In the absence of ascites, the mean serum creatinine level in cirrhosis was 1.43±0.33mg%, in hepatoma 1. 32±
0.39mg% and in chronic hepatitis 1. 14±0.35mg%. The data shows serum creatinine level is higher in the presence of ascites than in cases, without ascites in respective liver disease.
3) In 85 cases with cirrhosis, BUN, serum creatinine and abdominal circumference were roughly inversely proportional to total serum protein and 24 hour urine output in both ´groups with and without ascites.
4) In patients with cirrhosis, the BUN and serum creatinine level did not show close relationship with respective value of various liver function tests such as GOT, GPT, alkaline phosphatase and bilirubin level in both groups with and with-out ascites.
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KEYWORD
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