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KMID : 0377619870520110691
Korean Jungang Medical Journal
1987 Volume.52 No. 11 p.691 ~ p.694
Some Recent Advances in Biological Theory in Affective Disorders - Neurochemical and Neuroendocrine Dysregulation -


Abstract
Neuroendocrine function has been reported by several workers to be abnormal in affec-tive disorder and it has been shown that neurotransmitters are involved in the regulation of neuroendocrine function.
Depressed patients demonstrated deregulation in multiple neurochemical and neuro-endocrine systems, many of which are involved stress mediated reactions.
Thus it is very intriguing that neuroendocrine & neurochemical abnormalities in depres-sion that we have reviewed involve imbalance of neurotransmitters and deregulation of neuroendocrine that directly or indirectly mediate stress-responsivity in humans. But it is necessary to define how this deregulation becomes translated into the clinical phenomenon of depression as the further research method.
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