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KMID : 0378019890320020110
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New Medical Journal
1989 Volume.32 No. 2 p.110 ~ p.114
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Ketorolac Tromethamine as Compared with Dagafor Treatment of Pain Induced byAcute Soft Tissue Injury in Patients of Department of Orthopedic Sugery
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Abstract
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Ketorolac tromethamine, a nonnarcotic, prostaglandin synthesis-inhibiting analgesic, was compared with Daga° for relief of pain induced by Acute soft tissue injury (sprain, strain, & contusion).
The 60 patients participated in this study. The 30 patients were received Ketorolac tromethamine 40 ~ g per day for 7 days per orally in a randomized parallel study. The remain 30 patients were received Data 8 tablets per day for 7 days per orally.
The results were compared at the end of treatment in a respect of pain on motion, degree of motion limitation, side effects, physician´s overall effectiveness rating, & patient´s global evaluation. Results were as follows:
1. It showed more excellent result as regard the improvement of pain on motion, and motion limitations, in the group of Ketorolac tromethamine.
2. Physician´s overall effectiveness rating was more than good in 96.7%. 3. Patient´s global evaluation was more than good in 98.8%.
4. Three patients, who have taken Ketorolac tromethamine, were suffered from side effects such as 2 cases of abdominal pain and 1 case of nausea, constipation and abdominal discomfort. These symptoms were light and were recovered spontaneously or by medication.
Conclusion: The Ketorolac tromethamine was very effective for relief of pain induced by soft tissue injury (sprain, strain & contusion) in orthopaedic field, and side effects were few and generally mild.
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