Morphologic studies of red blood cells have been reported by many investigators for the past deades,
The method of blood smears for measuring RBC size is inappropriate because of artifact and poikilocytosis.
Receatly, an automated blood analyzer, Coulter Counier Model S plus Ⅱ was introduced and the RDIV was easily calculatea.
Therefore, this study was begin to evaluate the clinical significance of RDW by determining the RDW healthy person and various hematologic diseases.
The following results were obtained.
1. The mean value of RDW in 100 healthy person was 12.74.
2. The diseases that disclosed normal RDW and low MCV: ITP, hypochromic microcytic anemia due to chronic disease.
3. The diseases that disclosed low MCV and high RDIV: Iron del. anemia.
4. The diseases that disclosed normal MCV and normal RDW: Reactive marrow, Myeloid hyperplasia, Metastatic tumor and acute hemorrhage.
5. The diseases that disclosed high MCV and Normal RDW: Aplastic anemia, APL.
6. The diseases that disclosed high MCV and high RDW: ALL, CML, Refractory· anemia, hemolytic anemia.
From these results, RDW can be used as a valuable parameter in the diagnosis of various hematologic disorders.
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