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KMID : 0378119870140020513
Chungnam Medical Journal
1987 Volume.14 No. 2 p.513 ~ p.517
Effect of Several Intrathecal Analgesics on Postoperative Analgesia


Abstract
Intrathecal administration of opioid for pain relief became popular since Pert, et al (1973) reported the opioid receptor in spinal cord.
It is obious now morphine has prolonged and profound analgesic effect with few complication but Meperidine has relatively shorted and profound analgesic effect.
This study was taken to observe on effect of postoperative pain relief after intrathecal morphine (0.3mg) and meperidine (3mg) injection.
We selected 40 patients, divided into 2 group to compare the effects respectively.
Group ¥° : 20 patient receiving 0.3mg intrathecal morphine.
Group ¥± : 20 patient receiving 3mg intrathecal meperidine.
The results are as follow.
1) Duration of analgesia of group ¥° was 23.5¡¾5.6 hrs. and group ¥± 8.1¡¾2.3 hrs.
2) The side effects of group ¥° and ¥± were similar, but pruritis was noted twice as much as group ¥° than in group ¥±.
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