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KMID : 0380219930260050408
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Journal of Biochemistry and Molecular Biology
1993 Volume.26 No. 5 p.408 ~ p.412
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Effects of n-Alkanols on the Rotational Relaxation Time of 1,6-Diphenyl-1,3,5-hexatriene in the Model Membranes of Total Lipid Fraction Extracted from Brain Membranes
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Goon-Jae Cho
Hyun-Ok Jung/Su-Kyung Choi/Jung-Sook Kang and Il Yun
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Abstract
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The effects of n-alkanols on the rotational relaxation time of 1,6-diphenyl-1,3,5-hexatriene (DPH) were investigated in the liposomes of total lipids (SPMVTL) extracted from synaptosomal plasma membrane vesicles. n-Alkanols decreased the rotational relaxation time of DPH in the SPMVTL, and the potencies of n-alkanols up to 1-nonanol increased by 1 order of magnitude as the carbon chain length increased by two carbon atoms. The cut-off phenomenon was reached at 1-decanol, where further increase in hydrocarbon length resulted in an increase in the rotational relaxation time of DPH.
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