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KMID : 0381919970270040391
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Korean Journal of Microscopy
1997 Volume.27 No. 4 p.391 ~ p.402
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Ultrastructural Characteristics of Glomeruli in EGS/Kist Mice Showing High Proteinuria
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Lee Chul-Ho
Hyun Byung-Hwa
Jeong Young-Gil
Kim Moo-Kang
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Abstract
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Using the electron microscopical method, this study was attempted to investigate the ultrastructural characteristics of glomeruli in FGS/Kist mice showing high proteinuria. The mucus-like substances were observed in glomerular capillary lumen which were usually narrowed by the widening of mesangial area filled with electron-dense deposits. Some portions of basal lamina in capillary wall were projecting to urinary space. Moreover, many vacuoles were observed in the cytoplasm of visceral epithelial cells, and an irregular-shaped fusion or effacement of foot processes were often shown in areas adjacent to basal lamina of glomeruli.
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KEYWORD
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Ultrastructure, FGS, glomeruli
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