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KMID : 0382319910110020148
Environmental Mutagens and Carcinogens
1991 Volume.11 No. 2 p.148 ~ p.160
Pi Class of Glutathione Transferase is the Major Form of Detoxifying Enzyme in the Human Epithelial Tissues and Saliva
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Abstract
Localization of isoenzyme of glutathione transferase Pi class was compared in different human tissues by immunohistochemical analysis. Strong enrich-ment of GST-Pi in the epithelial tissues was observed in the granular layer of skin, nipple and esophagus which are vulnerable to exogenous chemicals and in the duct epithelium such as pancreatic, biliary, salibvary, renal tubules as well as in the steroid biosynthesis organs such as theca and granulosa of ovary, leydig cell of testis and zona reticularis of adrenal glands.
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