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KMID : 0382420010270040073
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Korean Journal of Environmental Health Society
2001 Volume.27 No. 4 p.73 ~ p.78
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Rat Skin Permeation Characteristics of L-cystein to Common Permanent Wave Drug In Vitro
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Kim Yong-Yeul
Yoon Cheol-Hun
Kim Nack-Joo
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Abstract
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Hair will be persuit of beautifulness of human being in various permanent wave by many kinds of its drugs. Skin is based upon the hair which enroll the body of high living animals and have multiple membrane structure. In this study used rat and the effects of commercial permanent wave products to skin which are composed with L·cysteine and bases. Results are as follows; the content of penetration 4 hours later with steady state and no significant changeable after 20 hours later. In cysteine groups lag time and permeability coefficient of healthy skin is 2.22hr and 0.103 ㎍/㎠·hr, lag time and permeability coefficient of old skin is 4.01hr and 0.108㎍/㎠·hr. In conclusion of study lag time and permeability coefficient in old skin and wounded skin are faster than healthy skin. We notified that fine rinkle and rash of skin were changeable in the case of treating with permanent wave drugs than normal skin.
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