KMID : 0388220140210040201
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Journal of the Korean Rheumatism Association 2014 Volume.21 No. 4 p.201 ~ p.204
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A Case of Rituximab Therapy in Diffuse Alveolar Hemorrhage of Systemic Lupus Erythematosus Refractory to Steroid Pulse Therapy
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Yim Sang-Woo
Byon Chang-Kyoo Park Jun-Yong Lee Sang-Yeob Chung Won-Tae
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Abstract
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Rituximab is a chimeric murine-human monoclonal anti-body that is directed against the specific B-cell CD20 anti-gen, which has recently been successfully used in active or refractory systemic lupus erythematosus (SLE) manifes-tations, such as nephritis, thrombocytopenia, and vasculitis. We report a case of a 25-year-old woman diagnosed with diffuse alveolar hemorrhage of SLE refractory to steroid pulse therapy. The patient was treated successfully with rit-uximab as a part of the immunosuppressive regimen.
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KEYWORD
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Rituximab, Diffuse alveolar hemorrhage, Systemic lupus erythematosus
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