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KMID : 0388220140210040201
Journal of the Korean Rheumatism Association
2014 Volume.21 No. 4 p.201 ~ p.204
A Case of Rituximab Therapy in Diffuse Alveolar Hemorrhage of Systemic Lupus Erythematosus Refractory to Steroid Pulse Therapy
Yim Sang-Woo

Byon Chang-Kyoo
Park Jun-Yong
Lee Sang-Yeob
Chung Won-Tae
Abstract
Rituximab is a chimeric murine-human monoclonal anti-body that is directed against the specific B-cell CD20 anti-gen, which has recently been successfully used in active or refractory systemic lupus erythematosus (SLE) manifes-tations, such as nephritis, thrombocytopenia, and vasculitis. We report a case of a 25-year-old woman diagnosed with diffuse alveolar hemorrhage of SLE refractory to steroid pulse therapy. The patient was treated successfully with rit-uximab as a part of the immunosuppressive regimen.
KEYWORD
Rituximab, Diffuse alveolar hemorrhage, Systemic lupus erythematosus
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