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KMID : 0390320140240010033
Chungbuk Medical Journal
2014 Volume.24 No. 1 p.33 ~ p.40
Pleomorphic Rhabdomyosarcoma of the Uterine Corpus in a 65-Year-Old Woman
Park Yeon-Jin

Hong Seung-Hwa
Ji Il-Woon
Jeong Eun-Hwan
Kim Hak-Soon
Abstract
Pleomorphic rhabdomyosarcoma of the uterus is an extremely rare malignant neoplasm with a poor prognosis. A 65-year-old woman presented with vaginal bleeding and suprapubic abdominal pain. A large necrotic mass prolapsed into the vaginal canal. Magnetic resonance imaging demonstrated a huge mass with heterogeneous signal intensity in the uterus. Radical hysterectomy including bilateral salpingo-oophorectomy and pelvic lymph node dissection was performed. Pathology revealed pure pleomorphic rhabdomyosarcoma of the uterine corpus, and the patient received 3 cycles of adjuvant chemotherapy using Ifosfamide and cisplatin. The patient was healthy until a sudden chest pain ten months later. PET-CT demonstrated tumor recurrence in her thorax and iliac bone. She died of massive hematemesis due to metastasis to the stomach. We present the first reported case of pleomorphic rhabdomyosarcoma of the uterus from South Korea, and suggest that PET-CT can be useful in the early detection of tumor recurrence.
KEYWORD
Rhabdomyosarcoma, Pleomorphic rhabdomyosarcoma, Uterine neoplasms, Magnetic resonance imaging, Positron-emission tomography
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