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KMID : 0390620160240040285
Journal of Cardiovascular Ultrasound
2016 Volume.24 No. 4 p.285 ~ p.293
Normal 2-Dimensional Strain Values of the Left Ventricle: A Substudy of the Normal Echocardiographic Measurements in Korean Population Study
Park Jae-Hyeong

Lee Ju-Hee
Lee Sang-Yeub
Choi Jin-Oh
Shin Mi-Seung
Kim Mi-Jeong
Jung Hae-Ok
Park Jeong-Rang
Sohn Il-Suk
Kim Hyung-Seop
Park Seong-Mi
Yoo Nam-Jin
Choi Jung-Hyun
Kim Hyung-Kwan
Cho Goo-Yeong
Lee Mi-Rae
Park Jin-Sun
Shim Chi-Young
Kim Dae-Hee
Shin Dae-Hee
Shin Gil-Ja
Shin Sung-Hee
Kim Kye-Hun
Kim Woo-Shik
Park Seung-Woo
Abstract
Background: It is important to understand the distribution of 2-dimensional strain values in normal population. We performed a multicenter trial to measure normal echocardiographic values in the Korean population.

Methods: This was a substudy of the Normal echOcardiogRaphic Measurements in KoreAn popuLation (NORMAL) study. Echocardiographic specialists measured frequently used echocardiographic indices in healthy people according to a standardized method at 23 different university hospitals. The strain values were analyzed from digitally stored images.

Results: Of a total of 1003 healthy participants in NORMAL study, 2-dimensional strain values were measured in 501 subjects (265 females, mean age 47 ¡¾ 15 years old) with echocardiographic images only by GE echocardiographic machines. Interventricular septal thickness, left ventricular (LV) posterior wall thickness, systolic and diastolic LV dimensions, and LV ejection fraction were 7.5 ¡¾ 1.0 mm, 7.4 ¡¾ 1.0 mm, 29.9 ¡¾ 2.8 mm, 48.9 ¡¾ 3.6 mm, and 62 ¡¾ 4%, respectively. LV longitudinal systolic strain (LS) values of apical 4-chamber (A4C) view, apical 3-chamber (A3C) view, apical 2-chamber (A2C) view, and LV global LS (LVGLS) were -20.1 ¡¾ 2.3, -19.9 ¡¾ 2.7, -21.2 ¡¾ 2.6, and -20.4 ¡¾ 2.2%, respectively. LV longitudinal systolic strain rate (LVLSR) values of the A4C view, A3C view, A2C view, and LV global LSR (LVGLSR) were -1.18 ¡¾ 0.18, -1.20 ¡¾ 0.21, -1.25 ¡¾ 0.21, and -1.21 ¡¾ 0.21-s, respectively. Females had lower LVGLS (-21.2 ¡¾ 2.2% vs. -19.5 ¡¾ 1.9%, p < 0.001) and LVGLSR (-1.25 ¡¾ 0.18-s vs. -1.17 ¡¾ 0.15-s, p < 0.001) values than males.

Conclusion: We measured LV longitudinal strain and strain rate values in the normal Korean population. Since considerable gender differences were observed, normal echocardiographic cutoff values should be differentially applied based on sex.
KEYWORD
Echocardiography , Strain , Normal population , Reference value
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